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Lactate dehydrogenase (LDH) is an enzyme present extensively in body tissues, such as blood cells, skeletal muscles, kidneys, brain, and lungs. The tissue levels of this enzyme are 500 fold higher than those normally present in the serum. Thus any cells or tissue damage elevates the serum level of LDH to a significant extent. Thus, increased LDH level in blood is generally an indication of cellular damage.
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