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Testosterone is a C-19 steroid secreted by the testis and adrenal cortex in men, and by ovaries in women. Hypogonadism in males and hyperandrogenic states in females can be clinically evaluated with testosterone measurements. Testosterone circulates in the blood bound to three proteins, i.e. sex hormone-binding globulin (60-80%), albumin and cortisol binding globulin. Unbound or free testosterone accounts for only about 1-2% of the total circulating testosterone. Alongwith diagnosing infertility and PCOD in females, diseases/ damages of ovaries, testes, adrenal and pituitary gland can also be screened using this test.
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